颅脑外伤急性期血糖、肌酐的变化与疾病转归的研究

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联勤军事医学 ›› 2017, Vol. 31 ›› Issue (05) : 297-0.

临床研究

颅脑外伤急性期血糖、肌酐的变化与疾病转归的研究

李慧¹,周杰²

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摘要

探讨颅脑外伤急性期血糖、肌酐的改变与病情转归的关系判断患者预后，指导临床提供理论依据。方法选取2014年10月～2015 年 10月来我院神经外科的71例颅脑外伤患者，按照病情计分法（格拉斯哥昏迷量表，GCS）将患者分为轻型组、中型组、重型组。观察不同时间点每组患者的血糖、肌酐的改变情况。结果颅脑外伤患者伤后血糖、肌酐均升高，重型组血糖、肌酐水平明显高于轻型组及中型组，具有显著统计学差异（p＜0.05）。轻型组患者伤后30d复查血糖、肌酐基本恢复正常，中型、重型组血糖升高持续时间长，伤后30d仍保持较高水平；中型组肌酐恢复正常，但重型组肌酐仍高于正常值。表明颅脑损伤GCS评分越低，血糖、肌酐值越高，持续时间越长。结论监测颅脑外伤患者的血糖、肌酐水平，对及时采取合理的治疗措施，提高此期颅脑外伤疾病救治成功率，指导临床工作。

Abstract

To investigate the relationship between the change of blood glucose and creatinine and the prognosis of patients with craniocerebral trauma, and to provide theoretical basis for guiding clinical prognosis. Methods 71 cases of patients with craniocerebral trauma from October 2014 to October 2015 were divided into mild group, moderate group and severe group according to the score of disease (Glasgow Coma Scale, GCS). The changes of blood glucose and creatinine were observed in each group at different time points. Results The levels of blood glucose and creatinine in the patients with severe traumatic brain injury were significantly higher than those in the light and medium groups (p <0.05). In the light group, blood glucose and creatinine returned to normal level 30 days after injury. The duration of blood glucose in medium and heavy group was longer than that in normal group. The level of creatinine in medium group was higher than that in normal group. Indicating that the lower the GCS score of craniocerebral injury, the higher the blood glucose, creatinine value, the longer the duration. Conclusion The monitoring of blood glucose and creatinine levels in patients with traumatic brain injury is of great significance in assessing prognosis and ly taking treatment measures to improve the success rate of treatment.

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李慧蔡忠林梁仲珍马莉徐倩孙建军周杰. 颅脑外伤急性期血糖、肌酐的变化与疾病转归的研究[J]. 联勤军事医学, 2017, 31(05): 297-0

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收稿日期	修回日期	出版日期
2016-11-04	2017-04-17	2017-05-28
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2017-05-28

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