血清降钙素原对老年胆石症患者术后并发感染的诊断价值

杨至宜 胡 塔

联勤军事医学 ›› 2012, Vol. 26 ›› Issue (04) : 339-341.

PDF(430 KB)
PDF(430 KB)
联勤军事医学 ›› 2012, Vol. 26 ›› Issue (04) : 339-341.
临床研究

血清降钙素原对老年胆石症患者术后并发感染的诊断价值

  • 杨至宜,胡 塔
作者信息 +

Clinical Significance of Serum Procalcitonin Levels in Judgement of Infection in elderly cholelithiasis after biliary tract surgery

Author information +
文章历史 +

摘要

目的 探讨血清降钙素原(procalcitonin,PCT)对老年胆石症患者术后并发感染的诊断价值。方法 选取老年胆石症术后继发感染的患者41例(感染组),术后未继发感染的患者50例(未感染组),健康体检者20例(对照组);观察三组间血清PCT、白细胞计数(WBC)及C-反应蛋白水平(C-reactive protein,CRP)。另动态检测5例术后并发严重感染患者的血清PCT水平,并观测其与预后的关系。结果 术后24h,感染组PCT水平明显高于未感染组和对照组(均P<0.001),而未感染组和对照组之间PCT水平差异无统计学意义(P>0.05);感染组CRP水平与未感染组之间差异无统计学意义(P>0.05),但都明显高于对照组 (均P<0.001) ;未感染组与对照组之间WBC水平差异无统计学意义(P>0.05),但都明显低于感染组(均P<0.01)。术后并发重症感染的5例患者中:3例患者的血清PCT值持续在较高水平(均大于13.8 ng/ml),最终抗生素治疗无效死亡,提示感染未能得到有效的控制,抗生素治疗无效;另2例患者抗生素治疗有效,其PCT水平随着临床症状改善呈下降趋势。结论 血清PCT水平对诊断老年胆石症患者术后是否继发感染有重要价值,可作为判断其预后的参考指标。

Abstract

[Abstract] Objective:To explore the clinical significance of serum procalcionin (PCT) levels in judgement of infection in elderly cholelithiasis after biliary tract surgery.Methods :41 old infected cholelithiasis after biliary tract surgery were collected as the infection group,another 50 non-bacterial infected patients were collected as the non-infection group,20 healthy volunteers were collected as the control group.Serum PCT、CRP and WBC levels were detected in the three groups on day 1,3,5 and 7. The PCT level of the 5 severe infected cases were detected dynamicly and observed the mutual relations between PCT levels and prognosis. Results :At day 1,Serum PCT levels in the infection group was obviously much higher than the infection group and the control group (P<0.001 and P<0.001 respectively),and there was no statistical difference between the control group and the non-infection group(P>0.05).CRP levels in the infection group and the non-infection group was no statistical difference (P>0.05),but all were much higher than the control group (P<0.001 and P<0.001 respectively);WBC levels in the control group and the non-infection group was no statistical difference (P>0.05),but all were much lower than the infection group (P<0.01 and P<0.01 respectively).3 of 5 severe infected patients was dead,and their serum PCT levels was always higher than 13.8ng/ml. Conclusions : The serum PCT levels in elderly cholelithiasis after biliary tract surgery was closely related to the severity of the symptoms.Therefore the alteration of serum PCT level may be used as one of the effective predictors for infection in in elderly cholelithiasis after biliary tract surgery.

关键词

老年胆石症 / 降钙素原 / C-反应蛋白

Key words

Procalcionin(PCT) / elderly cholelithiasis / CRP

引用本文

导出引用
杨至宜 胡 塔. 血清降钙素原对老年胆石症患者术后并发感染的诊断价值[J]. 联勤军事医学, 2012, 26(04): 339-341
Clinical Significance of Serum Procalcitonin Levels in Judgement of Infection in elderly cholelithiasis after biliary tract surgery[J]. Military Medicine of Joint Logistics, 2012, 26(04): 339-341

参考文献

参考文献
[1]李奉达,邱法波,刘宁.胆石病病人胆汁细菌学检查分析[J].世界华人消化杂志,2008,16(35):40044007.
[2]刘振声,金大鹏,陈增辉.医院感染管理学[M].北京:军事医学科学出版社,2000:477-480.
[3]刘静,牛爱敏。老年急性梗阻性化脓性胆管炎PTCD治疗的临床观察与护理[J].护士进修杂志,2008,23(15):14121414.
[4]杨世华.胆结石病患者胆汁细菌分布与耐药情况分析[J].检验医学与临床,
2009,6(4):287.
[5]廖扬,石玉玲,曾兰兰,等.降钙素原定量检测在鉴别细菌和病毒感染中的诊断意义[J].细胞与分子免疫学杂志,2009,25(12):1169-1170.
[6]石玉玲,廖扬,曾珠,曾兰兰,等.血清降钙素原在下呼吸道感染疾病中的诊断与应用[J] .中华医院感染学杂志,2010,20(1):44-46.
[7] 宋琼.降钙素原在ICU中的诊断与应用[J].河北医学,2008,14(5):626-628.

PDF(430 KB)

3204

Accesses

0

Citation

Detail

段落导航
相关文章

/